After a massive shootout, a mysterious stranger arrives at a local hospital on the brink of death. Then, a foreign gang brazenly comes to the hospital to hunt him down. His nurse, the sole surviving witness to the follow-up shootout, must face an FBI interrogation that unlocks a plot of international intrigue and revenge.

Phillip and Suzanne are retired from the spy game, living peacefully off the grid. That's until their whereabouts are discovered by Vlad, the vengeful brother of their target from the first film.