SIRIUS 6B, Year 2078. On a distant mining planet ravaged by a decade of war, scientists have created the perfect weapon: a blade-wielding, self-replicating race of killing devices known as Screamers designed for one purpose only -- to hunt down and destroy all enemy life forms.

A group of humans arrive on Sirius 6-B to investigate an SOS signal sent out from the planet, which has been supposedly deserted since the destruction of the man-made weapons known as "screamers." Once the squad arrives, they find a group of human survivors eking out an existence in an old military outpost.