United States President Lex Luthor uses the oncoming trajectory of a Kryptonite meteor to frame Superman and declare a $1 billion bounty on the heads of the Man of Steel and his ‘partner in crime’, Batman. Heroes and villains alike launch a relentless pursuit of Superman and Batman, who must unite—and recruit help—to try and stave off the action-packed onslaught, stop the meteor Luthors plot.

Batman discovers a mysterious teen-aged girl with superhuman powers and a connection to Superman. When the girl comes to the attention of Darkseid, the evil overlord of Apokolips, events take a decidedly dangerous turn.