The story, set in the backdrop of Nallore, a small town in Thoothukudi District, revolves around Sub-Inspector Durai Singam, a brave and just policeman who serves in his hometown primarily to fulfill his father’s wish. Durai Singam settles every dispute in his town patiently with his words of wisdom and resorts to force only when the situation demands it. Kavya, a city girl who comes on vacation to Nallore, falls in love with Durai Singam. Erimalai, Durai Singam's bumbling colleague and friend, often accompanies him.

Picking up the storyline from where Singam ended, Duraisingam has gone undercover after meeting the Home Minister and is working as an NCC officer in a school in Thoothukudi. The only people who know about this operation are the Chief Minister and Home Minister apart from himself.

A reputed cop from Tamil Nadu takes charge in Andhra Pradesh to solve the mysterious murder of a top police officer, and takes on local thugs and criminals during the course of his mission.

Sequel to Singam 3 (2017), the film will be directed by Hari