After a wave of reports of mysterious attacks involving people and pets being eaten by the traditionally docile fruit, a special government task force is set up to investigate the violent fruit and put a stop to their murderous spree.

Crazy old Professor Gangreen has developed a way to make tomatoes look human for a second invasion.

Police assitant Boyle along with tomatologist Kennedi Johnson look into investigations about Killer Tomato attacks, and discover Gangrene plans to brainwash people via TV talk shows to take over the world! Will Gangrene be stopped? Will Johnson become part of a Bacon, Lettuce and Human sandwich?

After being busted out of jail by his tomatoes, Professor Mortimer Gangrene begins a new plot to take over the world by inserting his hapless lackey Igor into the throne of the King of France.