When former Green Beret John Rambo is harassed by local law enforcement and arrested for vagrancy, he is forced to flee into the mountains and wage an escalating one-man war against his pursuers.

John Rambo is released from prison by the government for a top-secret covert mission to the last place on Earth he'd want to return - the jungles of Vietnam.

Combat has taken its toll on Rambo, but he's finally begun to find inner peace in a monastery. When Rambo's friend and mentor Col. Trautman asks for his help on a top secret mission to Afghanistan, Rambo declines but must reconsider when Trautman is captured.

In Thailand, ex-Green Beret John James Rambo joins a group of mercenaries to venture into war-torn neighboring Myanmar to rescue a group of Christian aid workers who have been kidnapped by a ruthless local infantry unit.

After fighting his demons for decades, John Rambo now lives in peace on his family ranch in Arizona, but his rest is interrupted when Gabriela, the granddaughter of his housekeeper María, disappears after crossing the border into Mexico to meet her biological father. Rambo, who has become a true father figure for Gabriela over the years, undertakes a desperate and dangerous journey to find her.