Erik Lund is a professor in child psychology. When his sister and her husband go on vacation, he is left in charge of their five children. He really feels up to it, since he is now going to be able to try out his skills in child psychology. However, reality is something else than theory and children do not always do as they are supposed to, according to his book on child psychology. The children soon fool him into doing as they please when it comes to food and pleasures. However, soon they start to realise that if they can make him serve them hot dogs and hamburgers and let them watch TV as much as they like, they can also make him help them restore their old house, so that they won't have to move, as their parents want to. And, as their uncle is nice enough to help them, they also decide to try and get him a wife.

Hele familien skal på skiferie i Norge, da far brækker benet. Derfor tager onkel Erik af sted med de fem ældste børn. På færgen møder Amalie skiinstruktøren Dan og onkel Erik bliver meget søsyg. Det viser sig far har lejet en meget lille utæt hytte, men Jan og Michael får det ordnet så de flytter ind i en stor suite. Det viser sig at den er udlejet til fru Flinth og hendes veninder og hun laver meget vrøvl. Familien smides ud, men igen ordner Jan og Michael situationen. De påstår at Erik Lund er en berømt sanger. Erik har travlt med at passe på Amalie, men da hun opdager Dans luskeri med en anden pige får hun drengene til at hjælpe sig. I mellemtiden får Erik også tid til at stå på skøjter sammen med fru Flint.

Five young siblings deal with a reluctant chaperone when they wind up stranded on a trip to Egypt.

My sister's kids this time are going to Jutland.

This time our already familiar family moves to Africa in order to save endangered wildlife.

Family film 'My Sisters Kids & the Gold Diggers' sends Uncle Erik and the kids on a new adventure. This time discovering the children that their great-grandfather emigrated from Denmark and was a gold digger in Canada. Even now, many years later, they still have family over there. So when the family comes in contact with an aunt, they travel across the Atlantic to visit her. In Canada awaits them a true treasure hunt, the wild and two greedy prospectors. At the same time they are joined by Mrs. Flinth which, as always, has a crush on Uncle Erik.