Two not-too-bright party girls reinvent themselves for their high school reunion. Armed with a borrowed Jaguar, new clothes and the story of their success as the inventors of Post-It notes, Romy and Michele descend on their alma mater, but their façade crumbles quickly.

This time around it's 1987, and new high school graduates Romy and Michele are desperate to get away from their hometown of Tucson. Their goal is to leave their square town behind and be amongst the beautiful, hip people of Hollywood.