Elphaba, an ostracized but defiant girl born with green skin, and Glinda, a privileged aristocrat born popular, become extremely unlikely friends in the magical Land of Oz. As the two girls struggle with their opposing personalities, their friendship is tested as both begin to fulfill their destinies as Glinda the Good and The Wicked Witch of the West.

Wicked tells the story of Elphaba, the future Wicked Witch of the West and her relationship with Glinda, the Good Witch of the North. The second of a two-part film adaptation of the Broadway musical.