Malick struggles to accept that he is now a patient for the foreseeable future. He pushes his son away and doesn't acknowledge that he needs counselling for his trauma. Meanwhile, Elliot is delighted to be working with his new mentee Zosia, but she proves to be quite a handful when she voluntarily decides to "psyche" a patient's mother - much to Elliot's chagrin. Elsewhere, Sacha feels uneasy about lying to Chrissie about his secret kiss with Mo. He decides to come clean to his wife, but realises that being honest isn't always the best policy.

Harry ends up on the wrong side of Gemma when an old friend turns up on AAU.

Mary-Claire tries to pull the wool over Harry's eyes but can she get away with it?

Malick is adjusting to life out of surgery when his old mentor arrives as a patient on Keller. How long will he be able to play by the rules and keep out of theatre? Sacha and Chrissie plan to renew their vows after she is given the all clear, but the moment is fleeting when both begin to question if they have what it takes to go the distance. The chapel is booked... The tension between Bonnie and Jac comes to the surface. Will either of them be able to bite their tongue?

Chantelle is torn apart when she is forced to confront her most frightening demon - Cameron. When Arthur professes his true feelings for her too, Chantelle realises she has reached a crossroads in her life... but what will she do? Mo is forced to face up to some bitter home truths when her online beau Joey is admitted with chest pains. Are her recent lifestyle changes becoming a threat to her career? Chrissie is suffering from post-treatment complications, so it is not a good day to be served divorce papers from Sacha. She seeks solace in a comforting Michael.

Overwhelmed by too much heartbreak, too many decisions and too many memories, Chrissie must look inside herself to find what she truly needs... but where will that lead her? Arthur struggles to cope as Malick spirals out of control - can he stand up to his forbidding mentor? Mo continues to face up to the gritty realities of her relationship with ex Joey... but when will she notice that Mr Right is eagerly waiting in the wings?

Malick is shocked to discover Jake is back working at Holby, but when a difficult case compromises them both will Malick step up? With a major incident and a particularly unusual case to handle on AAU, Serena has her hands full, but does the bigger challenge come from trouble at the top? Zosia is determined to prove her worth during the incident, but does she really understand the ways of the ward on Darwin?

Guy is determined to get stuck in to his new plans for Holby as CEO, but when he is confronted with familiar faces from his past, will he be able to give up his old ways? Jac is keen to impress the new boss at Holby and Jonny is determined to lighten Jac's load, but is Jonny taking too much? A suspected smuggler is making waves on AAU. Serena is brought in to deal with him, but soon it's not clear who's handling whom.

Mary-Claire is shocked to learn that Edward stood her up for his ex-wife Serena, and when challenged on it he bites back, eager to bury the fact that they had a relationship in the first place. Goading, she wonders what Serena would think if she found out; but when threatened, Edward gets nasty... Elliot goes the extra mile, having been encouraged by Guy to do an impromptu heart operation using the Herzig on a vulnerable patient. When he doesn't get the results he was hoping for in theatre, Elliot is troubled; his ego getting the better of him, and he's left with a deep sense of guilt for his young patient. Arthur's obsession with everything Chantelle draws to an abrupt end when Zosia, needing to find a new flatshare, bets him that he has to go a whole day without mentioning his ex-love's name, or she wil

Still reeling from Chrissie rejecting his offer to elope, Michael jeopardises his career when faced with a heartbreaking case. Michael goes all out in his attempt to save a father and his teenage son. When her mistake almost costs a patient his life, Gemma is forced to question whether she really belongs at Holby. Elliot is still in hiding after last week's Herzig operation ended badly. Fearing that Guy Self will use this as the perfect excuse to shut down his legacy, Elliot cannot face another patient. Unwilling to tolerate his self-pitying, Jac steps in and forces him to get back into surgery. Mary-Claire is left feeling increasingly isolated by Edward's snide remarks and accusations of incompetence. When a machine malfunctions on the ward, Edward is the first to blame her and questions whether she should be allowed near patients.

Serena and Edward arrive at work loved-up and energised, but when Mary-Claire makes clear she won't forgive Edward's treatment of her and their 'relationship', Edward is forced to confess to the affair. But is his drink problem as easily dealt with? Zosia is determined not to let her dad easily back into her life, but when a patient spots her lonely demeanour and gives Arthur some tips on a Polish Christmas, she finds herself with a smile on her face. A gift from her Mother is the icing on the cake. Mr Thompson is doing a great job of entertaining the patients in his Christmas elf outfit - so much so that it takes one of his delighted fans to point out the obvious to Mo - they'd make a great couple! Has she got the courage to ask him out?

Guy's failure to mend his relationship with Zosia has him finally admit defeat and accept his daughter's wish of keeping it purely professional. How long will it take until their feelings bubble to the surface? Serena is still blue from the humiliation she faced because of Edward's actions. With her morale at an all-time low, can she be brought back from the brink? Mary-Claire is finally putting the past behind her, but Harry just will not let it go. Will their friendship survive the recent Edward debacle?

Jac's delivery date looms. When she starts experiencing contractions ahead of schedule, Jac panics and the team on Darwin scramble into action. After a traumatic Christmas break, Serena returns intent on starting afresh. When she is surprised by Edward's return, Serena is forced to question her entire future. Ric goes back to his old university for an alumni ball. When he meets an old flame, he realises that life is never as straightforward as he thought it would be growing up

Colette is under some professional scrutiny. A controversial figure returns Whilst Jac and Jonny find it hard to cope as their baby's life hangs in the balance.

Emma is about to have her surgery as Jac attempts to defeat her demons and be there to support her daughter. Arthur and Dominic continue to clash with some potentially disastrous consequences.

There's a new registrar on AAU and he's determined to revolutionise the ward. When a patient arrives in a critical condition and the hospital lacks a vital piece of equipment necessary to save him, this wayward hero decides to build his own version. In an attempt to inspire his junior doctors, Sacha has arranged for a 2,000 year old Egyptian mummy to be scanned at Holby. But his plan backfires, when, under pressure from Guy to get Zosia interested in surgery, she expresses more interest in the mummy. Left with no choice, Sacha forces her into theatre, where her lack of dedication and skill nearly proves fatal. After three weeks, Jac is still unable to bond with her baby. Sick of her lack of maternal instinct, her paediatric consultant takes a stern approach, making Jac realise just how beautiful motherhood can be.

As Sacha continues to put Zosia, Arthur and Dominic through a punishing teaching schedule, Arthur begins to feel resentful of his new teacher. Dominic, meanwhile, would like nothing better than to take Arthur down a peg or two and impress Sacha in the process. When the two are assigned to the same case, the competition heats up. But when things take a turn for the worse, which young doctor will triumph? Serena is furious when she is sent to cover AAU, but a patient presents her with a business opportunity which may help Serena prove her worth to Guy. With her eye on the prize, will she heed Harry's warning that this particular patient is not all he seems? As Jac moves forward with her plans for Emma, Jonny is determined not to be left behind. With help from a familiar face, will Jonny be able to make his wishes heard?

When Harry witnesses dynamic Raf having a photo-call for a medical journal, Harry is determined to find a specialism. Raf rejects his attempts at joining his resus team, so Harry looks elsewhere. When a bariatric patient arrives Harry seizes his opportunity to shine, but at the expense of a far more severely ailing patient. On the day of baby Emma's christening, Elliot brings Jac the juiciest of cases - a heart condition not seen at Holby City Hospital in over a decade. Jac feels like she has to do it, but Jonny is dismayed that she would risk being late for the service for work reasons. When a patient with an abscess in his rectum refuses to be operated on by a woman, Serena and Zosia are forced to find a male surgeon. There is however only one man available to assist - Guy.

Zosia is excited when Sacha finally gives her the opportunity to prove herself with a psychiatrically vulnerable patient, but her own vulnerabilities are exposed as she struggles to grasp the severity of the case. Harry is frustrated when adoring bariatric patient Annie returns and does his best - however shoddily - to deter her, but it does not prove as easy as he had hoped. When Jac tells Jonny that her pay cheque dictates she has the right to make decisions about Emma, he resolves to get a promotion by exposing her as a bully.

It is Jonny's first day as the clinical nursing manager on Darwin. However, he is struggling to juggle all of his new duties. With Jac breathing down his neck, he is forced to assert his authority and use his new skills to help save the life of a vulnerable patient. Zosia, still reeling after the disastrous consequences of last week's surgery, has a new-found bond with her father. When Catherine O'Malley, a top transplant surgeon, arrives and Guy suggests Zosia assist her, Zosia can't help but feel Guy has an ulterior motive. It looks like Harry has gotten away with his reckless actions from last week. Rather than own up to his mistakes, Harry is busy making last minute holiday plans. However, Raf has other ideas for him.

Beth is still in a coma and Guy is determined to try and boost the Tressler Neurosurgical Foundation's profile. Dominic is determined to prove himself after showing up late for work.

Jess gets ready to undergo surgery as Ric finds it hard to step back as a doctor and let Serena deal with the case. Guy is feeling under pressure following the withdrawal of the Tressler fund.

uy is pulled up before the board after Zosia backs a patient's complaint against him. However, Guy is more worried about protecting Zosia's career than his own, especially when tensions mount and Zosia begins to crumble. The last person Zosia wants help from is her father, yet Guy is the only one who can give her the answers she so desperately craves. Are either of them ready to handle to truth? Ric's in deep trouble after covering for his daughter by claiming responsibility for David's accident. Ric is prepared to deal with the consequences of his actions, but when David plays a dastardly hand, is Jess as willing? Ric is pushed to his limits. As a surgeon, he follows a strict moral code, but as a father he'll do anything to protect his daughter. It's not long before news of Jonny and Bonnie's engagement gets out, and as Bonnie ploughs ahead with plans for the wedding, Jonny finds himself looking to Jac for her response. Will Jac finally let him go or stake her claim once and for

A new consultant pharmacist called Amy catches Harry's eye but they soon clash over the best way to treat a patient. Jac refuses to play happy families but after events spiral out of control during the hen party, Jonny decides that enough is enough.

Jonny and Bonnie's wedding day arrives but he still has lots of things to do before he's ready to get married. Zosia finds it hard to cope on the anniversary of her mother's death. Serena becomes obsessed with the new patient satisfaction surveys as she attempts to impress Connie.

Harry is agitated to learn that Raf's wife Amy is the new consultant pharmacist on AAU, but is intrigued to discover that their marriage may not be as perfect as it seems.

Raf and Amy are set to discover whether their final round of IVF has been successful. However, Raf soon gets consumed in a diverting case - a patient who has been technically dead for several hours but whom Raf believes is a candidate for a Lazarus-like resuscitation. Torn between his wife's emotional needs and cutting-edge medicine, Raf's priorities are tested and his marriage buckles beneath the strain.

The custody battle goes on as Jac plays dirty twisting Jonny's words and setting her lawyer against him. Arthur attempts to impress Guy and new anaesthetist Jesse.

Raf and Amy's relationship in under real pressure which results in a heart-wrenching betrayal. Jac finds the going tough as her past threatens to repeat itself.

Despite being on probation, Zosia is determined to move on and show Sacha she can keep up with the rest. But when an unusual patient raises her suspicions, can she prove that she has learnt from her past mistakes? Jonny is still reeling as Jac brings in the big guns in their battle for Emma. Jac's mum proves an unlikely ally in the fight, but does Jonny know he's made a deal with the devil? Dominic is sick of having his face rubbed in Arthur's successes and decides to make some bold moves of his own. However, when he finds himself on AAU for the day, will he be able to hack it on the front line?

Sacha quickly quashes Zosia and Arthur's concern over a patient with a suspicious past. As Sacha struggles to keep his junior doctors in line, will he be able to follow the rules himself? Jonny attempts to make amends to Jac as an incident in the hospital brings them closer together as parents - could this be the end of their hostilities? Adele proves she's got the gift of the gab as she assumes Mo's identity on a local radio show, but does she really know what she's getting into?

Serena has been really busy recently whilst trying to care for her mother, Adrienne. After Guy requests an urgent report outlining the hospital's chances of becoming a Neurosurgical Feeder Centre she's stretched to her limits. Elliot hasn't been feeling himself and keeps forgetting important things.

Amy desperately tries to put her mistake with Harry behind her, but her day takes an unexpected turn when she discovers she's finally got what she always wanted. However, she's forced to question at what cost when it's clear Harry is going to be in her life for a very long time. Serena's world is torn apart when her mother arrives at Holby and causes a near-fatal accident with her warden, forcing Serena to accept some painful truths about her mother's future. Meanwhile, desperate to escape Dr Mo, Adele finds her way onto Darwin. She finds herself immediately on the wrong side of Jac but with Jonny's help she manages to prove her worth and show her true potential.

While dealing with the consequences of recent events, Amy is caught in the middle of Raf and Harry's fractious personality clash. Guy offers to transfer Harry, but Amy decides to deal with him herself. Mo enjoys her celebrity status as Doctor Mo while being dismissive of Adele's career aspirations. Chastised by Adele for forgetting her mother's birthday, Mo has to reassess her priorities. And when a star-struck patient turns violent, she also has to acknowledge Adele's professional know-how. Guy informs Zosia that she has scored only 22 per cent for her bedside manner in a recent assessment. She needs to address her lack of patient empathy but has trouble with a patient who refuses pain relief. Jesse helps her raise her game.

A determined Amy throws her weight behind helping Harry shine. Jac's childcare nightmare gets worse when Elliot lends a hand.

Jac and Jonny prepare for their day in court, both determined to win Emma. However, Jac's carefully-laid plans are thrown into disarray by a powerful force from her past. Even at death's door Paula proves she still has the power to tie Jac in knots - will Jac rise above her machinations? With his divorce finalised and living at home with his mum, Sacha isn't sure his day could get worse, but when news that he treated a Nazi war criminal hits the front pages, Sacha puts his own feelings aside to go to Essie's aid.

Elliot finds a kindred spirit when he treats a shanty-singing fisherman.

Reeling from the news that Amy cheated on him, Raf demands that she take a paternity test.

Jesse's paranoia builds as Guy is on the verge of discovering his affair with Zosia.

Elliot is forced to confront his biggest fears on the day of the Herzig launch.

Elliot faces his fears about his brain surgery and decides to proceed despite complications, but his future at Holby may be in jeopardy along with his health. Raf resolves not to let what happened between Amy and Harry destroy his marriage. However, when he's asked to help advance Harry's career, he struggles with a painful decision. A disgruntled Herzig patient claims Elliot has been negligent. Jac effectively neutralises the problem, but in doing so has she protected his interests or helped undermine his position

Arthur struggles to keep Zosia in line when she gets emotionally involved with a patient. It is the end of term and Zosia drowns her sorrows with disastrous consequences. Raf's brother arrives on AAU and soon realises all is not well with Raf and Amy's marriage. When he is rushed into surgery, it is Harry who spots a potentially life-threatening complication. Relieved his brother has pulled through and taking his advice to heart, Raf realises the importance of family. Jac rejects Guy's offer of a promotion at Elliot's expense. But when she is teamed with former colleague, Connie Beauchamp, on a complex procedure, she comes to a momentous decision.

Mo feels the pressure of running Darwin as Zosia causes concern with her constant partying. Serena's mother takes a turn for the worse and she finds herself being confronted about it from all sides.

The new nurse arrives on the ward in the form of Fletch from the ED as Elliot returns to work.

As news of Jac's new appointment as head of cardiothoracics spreads, Elliot is gracious in defeat. But Jac, with a further twist of the knife, tells Elliot that he will no longer be in charge of the Herzig. Faced with the fact his Darwin daughter has stolen his life's work - can Elliot forgive her? Sacha and Essie are thoroughly loved-up and Dominic is pleased to benefit from Sacha's happy mood on the ward. However, the benefits are short-lived when Essie realises Sacha may be moving too fast. When a patient appears to recognise her from the papers, Essie is forced to consider whether she has really dealt with her past and is ready to face the future. Fletch assures Colette his new laissez-faire management style will be a breath of a fresh air on AAU after her jobsworth ways. Colette remains to be convinced that Fletch is taking the job seriously, and suspects he may have hired a new nurse for how she looks on the surface rather than her qualifications. Will the new addition to A

As Holby prepares for a big charity gala, Guy tasks Arthur with making sure an old patient of his gets the full VIP treatment on Keller, but when Zosia forms a close bond with the gentleman and pushes for a decidedly unconventional approach, Arthur is left scrambling in her wake. Arthur begins to wonder if Zosia is really coping. Jac is determined to make her mark on Darwin and when Mr T brings a special case to her attention, Jac throws herself wholeheartedly into the fray. As the rest of the team get caught up in the excitement of the high-stakes case, Jonny is the only one who questions what's really driving Jac's determination to bury herself in her work. When Billy Tressler arrives on AAU to observe Harry at work, Raf struggles not to let the Tressler family get under his skin.

Amy and Raf's conflicting feelings about the unborn child collide when they discover the sex of the baby. Still smarting from Jac's betrayal, Elliot takes on a patient's case against Jac's explicit instructions. Sacha's determination to make Essie happy forces her to make a brave decision.

With Arthur adjusting to the pressures of leading a team, his anxiety over Zosia brings him face to face with Guy, but what exactly should he tell Mr Self? Adele is intent on self-improvement, but an unimpressed Jac brings her down to earth, leaving Adele to think about her future at Holby. Facing increasing concerns from Ric, Fletch struggles to stay in control on AAU. Fearing his options are running out, he is grateful when support comes from a surprising source.

Raf resolves to give Harry a chance to prove himself. But when he sees an opportunity to undermine the ambitious registrar, he makes a dramatic intervention with disastrous consequences for Harry. After her traumatic break-up with Jesse, Guy's concerned for Zosia's health. But when he asks Amy to make an informal assessment, he is resistant to her professional opinion. When she notices women flirting with Jonny, Adele wonders if he is ready for a relationship after Bonnie's tragic death. Perhaps she knows a suitable candidate?

When Serena admits her mother to AAU, the women's relationship comes under scrutiny, particularly when Adrienne makes some damning allegations. And though she tries to keep them separate, Serena's personal and professional worlds collide with dramatic consequences. After ousting Elliot as lead consultant on Darwin, Jac has bridges to mend with the team. Instead, she antagonises Elliot by ignoring his advice and showboating with a daring surgical procedure. While his flatmates have busy social calendars, Dominic's private life is non-existent. But when a one-night stand - a nurse in a tiger onesie - offers the possibility of longer-term romance, can Dominic resist?

It's the day of Harry's hearing. As Serena prepares for the impact of the outcome on the AAU, events take an unexpected turn and a troubled Raf is challenged by an uncompromising vision of the future. Meanwhile, after losing the Herzig to Jac and moving out of the consultant's office, Elliot prepares for retirement but with Adele intent on keeping him at Holby, will he succeed with his plans? Elsewhere, with a loved-up Arthur and an absent Zosia, Dominic feels increasingly alone, until a surprising encounter with Kyle leads him to make risky decision.

When an erratic Zosia ignores the wishes of a patient, Dominic and Arthur worry about their futures. A loyal Colette risks much more than her career. Meanwhile, when a much-missed friendly face returns to AAU and offers support to a reinstated and grateful Harry, he demands answers to some awkward questions he can't afford to ignore. Elsewhere, when Jac catches on that Elliot is working on a new project, she is quick to get Guy involved. A wary Elliot fears he could lose out to Jac all over again.