Abbott and Costello do several of their burlesque routines with their usual supporting players. They also play as host to Luis Armstrong.

In one sketch, Abbott and Costello are offered a job on Cabot's dude ranch. On the way, they encounter Flynn, with whom they do the old "Niagara Falls" sketch. In another western bit, the boys have a run-in with bad guy Flynn. Rhonda Fleming performs "Don't Blame Me" and "I'm in Love With a Wonderful Guy".

Dean Martin and Jerry Lewis perform at the Mayhem Annual Awards Dinner. Jerry introduces Dean singing, When You're Smiling. We see the private lives of Jerry and Dean out of the public eye. Dean hires Jerry as a soda jerk. Guests: Ray Malone, Jill Jarmon, Danny Arnold, Sheldon Leonard, Mike Mazurki, Dick Stabile & his Orchestra; cameo by writer Norman Lear.

Hosts: Bud Abbott and Lou Costello Guests: Charles Laughton, Isabel Bigley, Johnny Conrad and his Dancers, Sid Fields, Joe Kirk, Milton Frome, Bobby Barber, Jill Kraft, Anita Anton, Alex Fossell, Helen Donaldson, Three Beaus and a Peep, Al Goodman and his Orchestra Note: Abbott and Costello do an ice cream vending skit and try to borrow money from Jack L. Warner. Isabel sings "Our Love Is Here To Stay." This show originated from New York.

Opens with Dean and Jerry as guests at a librarian convention. Followed by a sketch where Jerry plays a nut case, auditioning for a part in Dean's upcoming show. The final sketch has Dean and Jerry traveling abroad where Jerry plays a stowaway.

Bud Abbott and Lou Costello host this episode of The Colgate Comedy Hour. Their guests for this episode include ballet dancer and actress Vera Zorina, Broadway performer Tony Bavaar, The Ashtons, blonde beauty actress Monique Van Vooren, Sport Morgan, Sid Fields, dancer Gemze de Lappe, AC stalwarts, Joe Kirk and Bobby Barber, Jean Cleveland, Charlie Bollinder singers, Three Beaus and a Peep, and Al Goodman and his Orchestra. Comedy includes AC doing their Baccigalupe bit. Also, the boys visit France for a singing lesson.