When some human bones are found, Inspector Fabbri's team is called in for a forensic assessment. DNA testing concludes the bones are the remains of Alessandro Solferino, a young man who disappeared three years earlier. Fabbri soon discovers that the deceased's father, a wealthy businessman, has some skeletons in his closet.

Everyone is in shock when Chief Inspector Lorenzo Fabbri is killed by a car bomb during a trap set by a Mafia boss.

After the sudden death of Inspector Fabbri, Inspector Davide Rivera is called in to replace him.

Twenty years after fleeing to Brazil, following his involvement in a robbery, a mobster sends his son to Italy to get important documents from a safe deposit box. Soon after the young man collects the documents he is killed. Inspector Davide Rivera and his team are called in to investigate the murder.

Inspector Rivera and his team are called to the scene of what appears to be a suicide. Apparently, a member of White Brotherhood, a neo-Nazi movement, has jumped off an eight-storey building. But suspicion is raised about the suicide theory as the investigation links the case to similar deaths a few years before.

When a talented young athlete dies while competing in a swimming championship, everyone is shocked that his death was caused by a reaction to ephedrine, an illegal substance. Inspector Rivera and his team are called in to find out if the young swimmer took the substance of his own accord or whether he was the victim of foul play.

Inspector Rivera's former girlfriend, Sara, rings him seeking help. She's seen her partner Francesco hanging from a tree in her garden. But when Rivera arrives, the body isn't there, and his team begins to raise doubts about Sara's state of mind. A reappearance by Francesco causes Sara to question her own sanity.

After a raging night at a disco, Marco and his mates return to his car where they find the body of Marco's murdered father in the boot. Inspector Rivera and his team are called in for the usual investigation, but while Marco is the prime suspect, somehow things don’t quite add up.

Valentina Cavalli is a key witness in a conspiracy trial against a bank. On the day she is due to appear in court to testify, a gas explosion occurs in the flat next door to hers. The gas mains have been tampered with and it's obvious that someone wants her dead. But who is behind the attack? Inspector Rivera and Rex investigate.

In downtown Rome, three men are shot dead at the same time in three different spots. It's immediately clear that this is the work of a first-class marksman. But while two of the victims have no ID, the third one turns out to be a Colombian student. Something doesn't add up. Inspector Rivera and Rex are called in to investigate.

Inspector Rivera and Rex receive a strange visit from a war widow, who claims the ghost of her dead husband is responsible for the murder of a man and the bashing of another. The 'ghost' however is more - and less - than it appears to be.

When Clara is found dead in her husband's car after a crash, Inspector Rivera suspects that it was no accident and gets to work to investigate her death with the help of Rex. He finds everyone seems to have a good motive for killing Clara: her jealous husband, her lover, and the step-daughters who hated her.