Gary's hotel room burns in an electrical fire. While wondering where he is going to live, Gary also finds out that a greedy businessman wants to purchase McGinty's and an orphanage in order to demolish them and build a parking lot. Gary and Chuck must save McGinty's and the orphanage, and Gary must find a new place to live.

Gary must help a Vietnam vet who has the Congressional Medal of Honor when a ceremony in his honor triggers feelings of guilt because of a mistake he made in Vietnam.

McGinty's is asked to cater the wedding of Gary's ex-girlfriend, his high school sweetheart. Her romantic feelings are still somewhat directed at Gary, and what's worse, her father has been under police's witness protection for three weeks and the paper warns of criminal and violent actions at the wedding.

Gary must help a young boy who is ill with leukemia, but is refusing treatment. Gary learns about Jenny Sloane, a well-known woman who also has a terminal illness, and hopes Jenny will inspire the boy to receive treatment. Jenny's involvement with a self-absorbed Sun-Times columnist causes her to question her place in the public eye.

An old work friend of Gary and Chuck's plans to have plastic surgery to impress his girlfriend. Gary and Chuck learn that the procedure will kill him, and they plan to make him reconsider.

A young boy who is part of a youth basketball camp at a church is influenced by his older brother, recently released from prison. Gary works with a sister to keep the boy on the right path. Chuck struggles to find a new head chef for McGinty's and falls for a female applicant whose dishes are a little too unconventional.

The newspaper arrives with an article written in Russian Cyrillic text. Gary saves a cab driver from an accident (as seen in an English article), and finds that the cab driver can read Russian. They learn of an assassination attempt on a female Russian violinist who is playing at the Chicago-based Russian consulate.

After learning that a leader of a racist movement will be assasinated during a march, Gary begans to debate whether he should save his life or let him die. Marissa manages to convince him to save him, but the dilemma is further compromised when the leader's comrades attack and vandalize McGinty's. Now Gary has to stop the sniper from killing the leader of the movement. The situation is further complicated when the leader's son befriends a young African-American kid.

Gary is stressed out, and just wants a regular life. He is having recurring dreams about a psychiatrist, who encourages him to take Sundays off from the paper. Gary decides to take that advice. However, he finds out that he needs to convince a famous quarterback to stop playing in order to avoid a serious injury.

Gary comes between his cook and an accident-prone librarian. Chuck turns truthful while dating a Rabbi.

Gary's search for a missing child makes him a suspect. When the police won't listen to him, he goes into the flooding underground sewer to try to rescue the little girl before it's too late.

Gary must deal with a stowaway princess who hid in his trunk.

Gary tries to use his nomination to a public job to get a light put at a dangerous crossroad.

Gary has to keep an honest cop, Detective Crumb, from being arrested due to a blackmailed investigation.

Gary takes Marissa who poses as an Egyptian princess to gain admission to an exhibition so that he can save an archaeologist from being struck in the head by an ancient Egyptian stone. At the museum, Gary pushes the man out of the way only to see that someone wanted the archaeologist killed. The day after, Gary reads in the newspaper that there'll be a fire in the museum, so he checks up on a journalist who was at the museum the night the archaeologist was almost killed. When the eyes are stolen from a cat mummy, a curse is released causing everyone involved, including Marissa, to fall seriously ill.

After Gary is injured in a fall, he becomes housebound while his broken leg heals. In a ""Rear Window"" style plot, he watches people in the apartment building across the street and is attracted to a new neighbor who seem to have been the victim of a murder almost 50 years ago.

Gary's parents receive the paper when Gary is trapped in an abandoned theater trying to save a monkey. Gary's parents and Crumb accidentally bring together a family of Latvian trapeze artists in Chicago.

The paper sends Gary to save a man John Hernandez from getting killed in a road accident. After doing that the paper changes and it states that Hernandez is going to kill Rachel Stone the prosecutor who sent him to prison. Gary can't help but wonder why the paper sent him on such an errand. Gary then goes to the courthouse to stop Hernandez; Hernandez gets away and Gary is arrested and brought to Ms. Stone. When he tries to warn her about Hernandez; she doesn't believe him cause Gary won't reveal the source of his information. Hernandez got away by knocking Chuck out and taking his car. While Gary waits at the hospital, the paper now says that Hernandez is going to try again this time at her home. Gary goes there and gets him and Ms. Stone taken as hostage.

Gary learns that a British person who assisted him with a mission is actually a forger with many enemies.

Gary helps Renee, a woman who is being targeted by thieves.

While preventing a building from falling over and killing thousands, Gary is knocked unconscious and wakes up in October 1871, two days before the Great Chicago Fire.

Marissa sees a vision and thinks her sight is returning. Chuck witnesses a mob murder, and is in trouble. Gary, Chuck, and Crumb are taken hostage, and Marissa must save them.